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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67ffa9378920e748559e383afb8e87d9d5764482178695fab7cf1e31e0326b29' 
  AND token = '7nLoRWAnYAD4IbAcB+zm8BnPAUtlXFt0PGudlu0+BaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}