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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '425b45e555a17fe0d65de0cc30bd6df916b51e46d6e933c3670f22e7e7db03e0' 
  AND token = 'i8VBT8kpPuqfUFL85NfD1fItVEx+Pij0EgKL4xJ9gSQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}