SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b77b88200a093b51af0bfb6f2e8f42dbd2ce5b8fa0c361af3e7166480b20b747' 
  AND token = 'DXSc17zHdRbLeBD4GjpLl6o3/4MBAx+ppnLx+k/+/y8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}