SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '774886e961e49c56090e0cf20fb38f26640ab38b0e85e2af204df85851510105' 
  AND token = '1MceqO2uAlPF+lmDluc0vhmOU4JyLN59D7fMj7xPz8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}