SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8210824ec5cec6df4ff6805352db9c4f8f1d30a6fa0c3639b2e0ec27a062cc42' 
  AND token = '37Q9rMrBLEi3pLwy1MxUOOTdwOlfnSVYVwNzS6zMSmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}