SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07a0911cb6ee544da3f3bb91b40b2596836b4a5b16b32af619e3b06a2894c841' 
  AND token = '47zhpcaWZHXaY+UXlp3mO9KiAdI/ElvaE36JUXnsGwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}