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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '721ea809a01c5d9e601d4cd9a9f653c5fa8f98088be957719a39cad2819eb30d' 
  AND token = 'J3DABCJXm9f9rAxR9G+671g2PEWeQGK1NS8c27ypuPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}