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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27bdc385ea00fb840818bca8b6692dfec4c66ee4c3a39913d2c2e21df9c5baf8' 
  AND token = 'FFD43pUrifVx1qlV9Mfp5d2SJDf0rNTUrfPIzE623WY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}