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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e140277a6a53c50385e95f26de4d29da9de7543e12ee39a1cc3fc0d4707e7333' 
  AND token = 'b41ltyNaEtqqwk/0/iajTsurYYkyif7Ib+Mz17KBKvo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}