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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cec973ad67cb9d90004a0efcfffb25bc5e6fdd7761af1665890c81cb5c64fd65' 
  AND token = 'JVTIl+AdQBZ9RgIAO68yHI7BIoaJqlvDdbi3D6KwPXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}