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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fb6e38f1a7fa480e3a3005b14df285e5f5c8a01ff9a1fe36d71c0b9b9e73fcd' 
  AND token = '1b0K8dPDRHU9D8aqDWvyxNWVbPa8Pp4FDPNfbNNSL1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}