SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6726d6cbcd78cb0360e645ac128209da950e5f5d8769bf9c09a5a892f3cd2e78' 
  AND token = 'mcY683jmdjAhCn5z/LoqgLNSRVC+IfecHcdwAMl3V5U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}