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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5027608f3b72e38382d68947a9029abce51746e4c0b06881e7ee784ae5eb051b' 
  AND token = 'QB9ypUwlpKvVr4S/UC+iBXrHdCgoWcCqYcCkO/6kNHE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}