SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a2b0cbb011be05b0bba1b54993a63adfdd93f65afa4bf32b6b04205e0620e80' 
  AND token = '1LV9fOJfleAxVk7WSIFKuRLpw75qw+hqfRIbNrow7b8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}