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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b1acec88d013d9b962f1d926cfc46f0de32d9b13d172b6b3164cd0f39ef905a' 
  AND token = 'VWSUb0fKw6WYVRV6HBEx0c25BeW+OCqTWStvLK4iU8o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}