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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5a8f2c635945f1acb306ceb96c95008286cd0897463a0dc3132f2c1c74e7c4e' 
  AND token = 'BkEzmv/iGz2SJlmnrA5HSE+T5vB3OvX1kfqTUNFIb9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}