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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ed0fd63be2f64aeae4a8ed3d0a9a38575aa149daedff81b44e130c5d32d252f' 
  AND token = '9/Zw/zChhhAn9A+dxEo5VDFdrXJgIBiHKpMMhIYH3FE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}