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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af7e49f41b32d4076a0f9cfd6b3ea055be3126fa8367f5dd21e8a37e13043dc8' 
  AND token = 'bfW9Y7fhCNBgNaoxcRDOm+gpK6UXnGZTORpw2+a4WpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00202

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}