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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6dc90669b752c2fac46d0494cf44827b1459ab00200b50aabe9442625659e6b6' 
  AND token = '2R/lF7DZYKh7czTGZqtNOM7yxQKmt9SC0tR75nweFKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}