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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '486bb18f2d806d66d0be328231b4c1f520e00639c63106f8b83db7a964b0a5be' 
  AND token = 'feZkPRO5h6Y/Vd0TKbgwQBCDJfrOZBLf8RDdTz7v5Zo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}