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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a799cfd52e9e620f0def11afa1a89cba57ca65c12709d7a4c882d1938106a1f' 
  AND token = 'KP87YvSaW8p2TBHO4MYQQjE0EG5g5ozLFIPEcOAgsws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}