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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '757aa700a212a3b02727fe1a75dc9598ebce375fce23d494ab5521611c71cb35' 
  AND token = 'GYhZw1cHhjIsgZfd4V4FC0RDHNVNjxhVRzcuyZOC8rE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}