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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6844819fe6ea9ef61e4e02c34f37da55abc702e784ad633441ef0d6162e0f8a6' 
  AND token = '9VBTZv6vqnN8i4yCgg64wZ70tdEjrrMSC/KeZ7t9wsI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}