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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc6d1157eeebddb34f6e490edbc229bfc540a5b0eedb33a9bef5cc611167040f' 
  AND token = 'QVAqhLKG4wVKD3A9FaIoqyn0aTUg6yEGKfWDnc+IKdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}