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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec8d71ba364f5d7d12ec23fe29a46bf02bdad58d069fbdd2af6bee2094401b49' 
  AND token = 'bFQz7bgD63/iXiRPu9CKUSHDgta6EJ1zQmDKLXW0iD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}