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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39c0d1193c2816bb4451c45dca2e482cce02dda498a0196ef1dadd369b30dd44' 
  AND token = '5W+cwWooWDkYX/fJPUhi3AgJMi1LBWdtE41SMW31IL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00069

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}