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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65974e3af97a405bec57b292ed9bf3d68c2fb2484d01073d7d918f07be1ae268' 
  AND token = 'qyyYx/c80xajc5mytsI4C3/VGRAXnZHIfPT8ws2Q1a0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}