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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b22a5ac84f3b9896aeed5fdfebe506a3a6af7b265d55b21055fbf70d26e2541d' 
  AND token = 'VOxbk2MVrhsP9KRDE5AzO6sBS3tYsA/5nC5kC0GG7Zk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}