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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4541a8ac66c757df6794e11b0fca4b130c9bdec68d5d9b018ae8e2bf2d29ca95' 
  AND token = 'bH4R8p6LjlXzdh3+xf3Pz7fZ2yEjhMyZr48dtul5N9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}