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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acfa387a1b270aad3962b753044143b18071d01c5eba62226779f1f7c2d220bd' 
  AND token = 'uKLX6SApAFpuTP/uMODywCfyOIwbdYYuvyAs3M5uBiE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}