SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13cf63e1054e893b42dd96c0836d2cdff42dcca9134b2d412db920e3cc03eeef' 
  AND token = 'DIlkBTbDzO679s2mzLDLoa+1R21u1kP8LxHsjZR1e5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}