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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39eeff4e06fd6af5a389b121767af7d10bf559fad77007798ee7700e971c62e8' 
  AND token = 'TdnVcvBYZcCJheTPZK9urhTaLnSvKnDWWuUh2S6/qWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}