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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d55774ee0d2ab97b6f54c370e2a55a9d9e200b58b8a768976c40815f90c9369' 
  AND token = '+SfEmrmIPIM5f1afYUQ8bg+XJ0CdSc8nk4A4HtSVoBM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}