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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d5ef27eb58d41295366f4118d09733deb1182c2caa28a9a669df2c5f562b236' 
  AND token = 'A4JqJRYtH6YaRZo4Z2OA928fLW9lAQGVhKz0uPb+4H0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}