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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fea8b8de1c82efe3275ffed289fe44680d7b996134d6b7f065a894544ba0c807' 
  AND token = 'NfxPY5aQbZnj457Eps+MoxxHCuNtj2qjLytK/t8qhiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}