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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f3549715b7aee949fd1215cf2c3c99960abf4f742b3b3bfc259dd5cf5642f87' 
  AND token = 'Vol+GLCsY8cRfWjBkMf3EEu4qwlD3q5ISbcsgaKC5QY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}