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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad269aa0a36bb991fa4da41161daf138cc3e47bbe21674dad7f45b008adc2188' 
  AND token = 'rshSvt9tyjVVsNgRh8X0bMTiwmeUnpNc91B9Ti8/+Ck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}