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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47a3e771b42cdb86970f8897f7df7d7380ceb2e9408a6be6f61e0116d43df273' 
  AND token = 'lUXFMyqCVTEDCp07x5dtWuy6NqEsxZB3StUEwPjRDbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}