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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4115d749cc3154333013f38a8c568aaf32888a71f86e72eb8da46035a57deaf6' 
  AND token = 'Aw1HzgOr9x8+jdfpd1e7rdqND28E5oi+8DylBtvpikg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}