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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '048130ff2adff72cab619b39c975bbbf2bb7ca96207bca1c5102645f508abc9e' 
  AND token = 'Z5nYbvsU03Ruwc6pmxXZaNtHRec1P32aCwZElE7d0P4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}