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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23f2f2a0d6deb91e543213cb0d6b0c9193824cd5e04211401954055cee89f666' 
  AND token = 'IFrKNtUSkRxez0DRfr8vSwtpwJPdvNCSnNnvwn+pvAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}