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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f66a7bfb47c59be35f2dea1be03b0b7a1827d7ab56148834dcd78774e7d3c242' 
  AND token = 'HVZpDWaZ/Jmg37cCIkFX7RqQ8FMYnMjsgPei3Th73b8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}