SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '674b8d7d6bac9f84e2e05dfa8538f9dfe385b8252a3e893385170ac2bae4d257' 
  AND token = 'V/Ea2oc7vg3Pzb31mjef66Tp0GPk3UVEJ6rAG/P4EK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}