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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cf272d7c122bca6500067bb2cc3081e8c8d4d0426d3cfab1436007793d5d0a4' 
  AND token = 'WLcsNja66b27EwYtVrL2GdG/aOAUbMxNTeurvW0CYxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}