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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48f4a5690880fbd01ec807c23c518355d8dffe7852af1a2f7ba2dbe3dd459497' 
  AND token = 'S9czPF/udjoE9BeY+485noLdqGMGSyug1jRy2y1ml2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}