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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5001eda10c1d9c2bb523801390b82c6be8250593ef2fdb0e5119a7b05b7f0d4' 
  AND token = 'VfkxmcThskEzoyr41nRg/keXnfeGu051mfOcCpdWYOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}