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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7a733ced931f25f83c09acc31d639c66c4b7cd99769ecc335b6ac2cc09aa5ae' 
  AND token = 'R/NVRN5Q5ezYDMXfm9w3BKT9uaXi65jmA6SfgHa+zgc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}