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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2018fcc82dc38b1904e7d98ef15d4d3ac2eae5c23073dff4e7e7733608806bb3' 
  AND token = 'WE1LNe+MTStpJPZLqBl3tSMbR8/4hmOkECRovpYWrWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}