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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c961a11e5c79d0184ddd93675033852036c87f29a7fc912fcefe3a0e0bef4e3c' 
  AND token = 'PGdT8rUQ5sRT5Seu0mp+Lr2YtqDBUZ485jNNwsW9Rk4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}