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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e663a0544a254eafd6c69aa744f7b00bb17cb5420e8399d9e7f96e81b5ab8e0e' 
  AND token = '+tF/9YA/uGBz+j2+G+B0SSEHXregHy5O8UaRAa8dtQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}